Gleevac CAS NO.220127-57-1

Henan Wising Chem Co., Ltd is a national high-tech enterprise with a passion for selling and an emphasis on customer care.

We are committed to providing quality chemical products that help us become one of the most reputable, reliable and leading chemical products suppliers in the domestic and global markets.

We purpose to bring our value clients the best quality products, the most competitive prices, the shortest delivery and the best service.

Our customers include BASF, Bayer, Merck, AstraZeneca, Sun Pharma, Shanghai Pharmaceuticals, MSN Laboratories, Unither Pharmaceuticals, Cadila Healthcare, and Abbott, Amgen in the US.

Wising Chem is a reliable distributor in domestic and global markets, we own an excellent reserch team based on Zhengzhou University, Shanghai Medical College of Fudan University and Henan University of Animal Husbandry&Economy, we focus on Pharmaceutical intermediates, API, rare chemiclas, and fine chemicals.
 

Imatinib mesylate inhibits Bcr-Abl tyrosine kinase at the cellular level both in vitro and in vivo and selectively inhibits proliferation and induces apoptosis in fresh cells from Bcr-Abl positive cell lines, Ph chromosome-positive chronic granulocytic leukaemia and acute lymphoblastic leukaemia patients. In addition, imatinib mesylate inhibits platelet-derived growth factor (PDGF) receptor, stem cell factor (SCF), tyrosine kinase of the c-Kit receptor, thereby inhibiting cell behaviour mediated by PDGF and stem cell factor.